Polynucleotides are natural compounds derived from DNA and RNA fragments. Polynucleotides stimulate cellular regeneration by providing the skin with the necessary building blocks for collagen and elastin production.

Polynucleotide injections are administered through a series of microinjections into the skin, this minimally invasive approach reduces downtime and discomfort.

When injected into the skin polynucleotides signal two all-important changes to the way the skin behaves. First, it acts as a wound healing agent telling the skin to up regulate its repair mechanisms. This increase in cellular activity in the skin results in intense rejuvenation leaving the skin more supple with a marked reduction in the appearance of fine lines and wrinkles and other signs of aging.

It also has an anti-inflammatory effect, which means it reduces the negative effects of histamine on the skin which in turn allows the skin to focus on boosting cell renewal by increasing collagen production, improving elasticity and hydration.

Polynucleotides are commonly used to rejuvenate various areas of the face and body particularly in hard to treat areas such as the eyes. They work hard over a period of time to improve skin texture and health. We love them at SAS Aesthetics because they are rapidly becoming our treatment of choice for addressing traditionally difficult to treat like crepey skin and protect you against free radicals.

At a Glance

At a Glance

Downtime:

24-48 hours

Treatment duration:

30 minutes

Aftercare:

Avoid alcohol, smoking and hot showers for 6 hours. Avoid direct heat to the face for 7 days. No exercise for 24 hours.

Results can last:

Permanent - your skin is continuously ageing and repeat treatment is recommeneded to fight the signs of ageing every 6-12 months

Common side effects:

Minimal - mild redness, swelling and bruising can occur.

Treatment comfort:

Mild - topical anaesthetic is applied

Price:

From £400

Polynucleotides

Polynucleotides are natural compounds derived from DNA and RNA fragments. Polynucleotides stimulate cellular regeneration by providing the skin with the necessary building blocks for collagen and elastin production.

Polynucleotide injections are administered through a series of microinjections into the skin, this minimally invasive approach reduces downtime and discomfort.

When injected into the skin polynucleotides signal two all-important changes to the way the skin behaves. First, it acts as a wound healing agent telling the skin to up regulate its repair mechanisms. This increase in cellular activity in the skin results in intense rejuvenation leaving the skin more supple with a marked reduction in the appearance of fine lines and wrinkles and other signs of aging.

It also has an anti-inflammatory effect, which means it reduces the negative effects of histamine on the skin which in turn allows the skin to focus on boosting cell renewal by increasing collagen production, improving elasticity and hydration.

Polynucleotides are commonly used to rejuvenate various areas of the face and body particularly in hard to treat areas such as the eyes. They work hard over a period of time to improve skin texture and health. We love them at SAS Aesthetics because they are rapidly becoming our treatment of choice for addressing traditionally difficult to treat like crepey skin and protect you against free radicals.

Treatments — Face
Polynucleotide injections feature image headshot SAS aesthetics

At a Glance

At a Glance

Downtime:

24-48 hours

Treatment duration:

30 minutes

Aftercare:

Avoid alcohol, smoking and hot showers for 6 hours. Avoid direct heat to the face for 7 days. No exercise for 24 hours.

Results can last:

Permanent - your skin is continuously ageing and repeat treatment is recommeneded to fight the signs of ageing every 6-12 months

Common side effects:

Minimal - mild redness, swelling and bruising can occur.

Treatment comfort:

Mild - topical anaesthetic is applied

Price:

From £400

Before / After

Before & After

Frequently Asked Questions

How often should I repeat the treatment?

Initial treatment consists of 3 sessions spaced 2-4 weeks apart. For optimum results, repeat the treatment every 6-9 months.

What are the benefits?

Polynucleotides stimulate collagen and elastin production which improves skin texture, firmness, skin hydration, minimises the appearance of fine lines and wrinkles, promotes collagen and elastin production.

Is it painful?

We apply a topical anaesthetic to the skin prior to the procedure. This makes it a relatively pain-free treatment.

Are there any contra-indications?

Yes, the absolute contra-indications are pregnancy, breast feeding, fish allergy. Relative contra-indications are the use of blood thinning medications (please discuss this with your doctor during your consultation).

What is the difference between Fillers and Polynucleotides?

Dermal Fillers add volume to the face. For those who want to target the loss of collagen that results in skin sagging, fine lines and wrinkles, skin texture and health without having to add unnecessary volume. Polynucleotides is highly recommended.

What are polynucleotides made from?

Polynucleotides are biopolymers – stretchy molecules made from fragments of fish DNA extracted from salmon or trout which closely resemble human DNA.

As Seen In...

Patient Testimonials

Patient Testimonials
Patient Testimonials SAS Aesthetics

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I treat skin every single day. 

Here is what I wish more women knew before they came to see me.

1. The biggest change in your skin after 35 is not at the surface. It is structural. The products on your shelf can support it ,but they cannot rebuild it.
2. Most women I see are doing too much. Layering actives that cancel each other out, stripping a barrier that is already struggling. 
3. SPF is the most powerful anti-ageing tool you have. Wear it every single day and reapply throughout the day.
4. You cannot out-product a poor lifestyle. Sleep, nutrition and movement do more for your skin than anything you can buy.
5. Your neck and chest are ageing faster than your face, and most people completely ignore them. Start treating them now.
6. Price is not a marker of efficiency. Some of the most clinically proven ingredients cost almost nothing. Most of what you are paying for is marketing.
7. Strong actives are not always better. Most skin issues I see come from overuse, not underuse. If something is irritating your skin, it is damaging your barrier.
8. Your skin at 40 does not need the same routine it needed at 25. Most people are following advice built for someone half their age.
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