Polynucleotides are natural compounds derived from DNA and RNA fragments. Polynucleotides stimulate cellular regeneration by providing the skin with the necessary building blocks for collagen and elastin production.
Polynucleotide injections are administered through a series of microinjections into the skin, this minimally invasive approach reduces downtime and discomfort.
When injected into the skin polynucleotides signal two all-important changes to the way the skin behaves. First, it acts as a wound healing agent telling the skin to up regulate its repair mechanisms. This increase in cellular activity in the skin results in intense rejuvenation leaving the skin more supple with a marked reduction in the appearance of fine lines and wrinkles and other signs of aging.
It also has an anti-inflammatory effect, which means it reduces the negative effects of histamine on the skin which in turn allows the skin to focus on boosting cell renewal by increasing collagen production, improving elasticity and hydration.
Polynucleotides are commonly used to rejuvenate various areas of the face and body particularly in hard to treat areas such as the eyes. They work hard over a period of time to improve skin texture and health. We love them at SAS Aesthetics because they are rapidly becoming our treatment of choice for addressing traditionally difficult to treat like crepey skin and protect you against free radicals.
24-48 hours
30 minutes
Avoid alcohol, smoking and hot showers for 6 hours. Avoid direct heat to the face for 7 days. No exercise for 24 hours.
Permanent - your skin is continuously ageing and repeat treatment is recommeneded to fight the signs of ageing every 6-12 months
Minimal - mild redness, swelling and bruising can occur.
Mild - topical anaesthetic is applied
From £400
I have built SAS Aesthetics over the last decade with your safety and results in mind. Having worked as a surgeon I’ve developed a real knack for developing unique techniques that promise natural but meaningful results. I’m genuinely excited by the advances in aesthetic medicine and can’t wait to offer them to you as my patients.
Dr Adé is a surgical doctor with a specialist interest in plastic surgery and cosmetic medicine. After graduating the University of Exeter Medical School in 2020, Dr Adé has increased her experience through a variety of clinical settings. Dr Adé was inspired to increase her range as an injectables doctor due to her keen eye for aesthetics and passion about helping people feel their best selves. In her spare time, she engages in charitable work, travels and focuses on wellness building.
My name is Cristina, and I have been working hands-on aesthetics for more than two years now. However, my passion for skin, skincare, and understanding ingredients has been with me my entire life. I’m currently working alongside Dr. Mahsa at SAS Aesthetics where I truly connect with the result-driven and holistic approach we take. This perspective allows me to combine my love for achieving visible results with a focus on overall well-being, helping clients feel confident and radiant in their own skin.
My name is Jessica and I bring over a decade of experience in the beauty industry —a field I am truly passionate about. As a Level 4 trained therapist, I am committed to helping clients look and feel their best, empowering them with confidence. At SAS Aesthetics, my goal is to provide a seamless client experience within a welcoming and uplifting environment. I am dedicated to ensuring that every client leaves feeling rejuvenated, inspired, and like the best version of themselves.
Initial treatment consists of 3 sessions spaced 2-4 weeks apart. For optimum results, repeat the treatment every 6-9 months.
Polynucleotides stimulate collagen and elastin production which improves skin texture, firmness, skin hydration, minimises the appearance of fine lines and wrinkles, promotes collagen and elastin production.
We apply a topical anaesthetic to the skin prior to the procedure. This makes it a relatively pain-free treatment.
Yes, the absolute contra-indications are pregnancy, breast feeding, fish allergy. Relative contra-indications are the use of blood thinning medications (please discuss this with your doctor during your consultation).
Dermal Fillers add volume to the face. For those who want to target the loss of collagen that results in skin sagging, fine lines and wrinkles, skin texture and health without having to add unnecessary volume. Polynucleotides is highly recommended.
Polynucleotides are biopolymers – stretchy molecules made from fragments of fish DNA extracted from salmon or trout which closely resemble human DNA.
Dr Saleki is the sweetest and most professional Dr ever! I was really nervous and she completely put me at ease for my fox eye thread lift!
I was a bit nervous, Dr Mahsa was lovely, she couldn’t of been more professional and kind. I had nose threads and the procedure was quick and apart from a bit of discomfort with the anaesthetic, the rest was totally pain free. I am 3 days post treatment and still a bit swollen but other than that everything has been very smooth and I feel fine. I’m excited to see the settled results. Would I recommend, 100% yes.
First time I every had any treatment and it was a brilliant experience, The Dr was very Calm and compassionate and clear. I read about a treatment threading but she said I didn’t need it and suggested fillers and fat dissolving which has work for me, definitely go again even though it took me over 2hours to get there.
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Non - surgical lower face rejuvenation. Restoring the elasticity of the skin is usually the first step in your journey to reversing aging. We love this transformation of lifted naturally volumised jowls and jawline 🥰Call today to book your appointment ☎️ #sofwave #polynucleotides #sylfirmx #skinlifting
Tox for wrinkles in the upper face is irreplaceable - period.Comment 💯 if you agree //#antiwrinkleinjections #crowsfeettreatment #wrinklerelaxing
Thinking about skin tightening but worried about doing it in the summer? That’s exactly why Sofwave is one of our go-to treatments for the warmer months.Unlike lasers that can increase sun sensitivity or require downtime, Sofwave uses ultrasound technology to stimulate collagen deep beneath the skin without damaging the surface. That means no peeling, no flaking, and no need to hide from the sun — perfect if you have a busy summer schedule or plan to be outdoors.Sofwave works by heating the mid-dermis (about 1.5mm deep), triggering your body’s natural collagen production for firmer, lifted skin over time. It’s safe for all skin tones, has minimal to no downtime, and you can apply makeup and get back to your day right after treatment.So if you want to address mild to moderate skin laxity in the brows, jawline, neck, or under the chin — but don’t want to press pause on summer — Sofwave is a smart, season-friendly solution.Your skin can still glow and lift this summer — without sacrificing beach days.#Sofwave #SkinTightening #SummerSkin #NonInvasiveLift #CollagenBoost #NoDowntime #UltrasoundFacial #SkinGoals
Have you noticed the skin on your arms? Be it acne scars, crepey thin skin or just a little too much fun in the sun. Your arms can give it all away! A couple of sessions of CO2 might be all it takes for that gorgeous glow to match your perfect summer outfit 💃DM to find out more ✨#bingowings #armtreatments #bodyskintightening
Want to lift the middle of your brows but not sure what the right treatment is?Get in touch with us today for a complimentary consultation#toxlift #foxeyes #browift
Let’s talk Sylfirm X and one of its most powerful features: the difference between pulsed wave and continuous wave RF — and why it matters for your skin.Sylfirm X uses dual-wave radiofrequency to treat everything from redness and melasma to skin laxity and texture.Pulsed Wave (PW): This mode targets abnormal blood vessels and pigment without damaging surrounding tissue. It’s perfect for conditions like melasma, rosacea, and post-inflammatory hyperpigmentation (PIH). The short bursts of energy allow for controlled delivery, calming overactive vessels and pigment cells.Continuous Wave (CW): This delivers a steady stream of RF energy deeper into the dermis, triggering collagen remodeling, skin tightening, and overall rejuvenation. It’s ideal for wrinkles, sagging skin, and large pores, helping to firm and lift over time.The beauty of Sylfirm X is that we can customize treatments by switching between the two modes based on your specific skin concerns. One device, multiple layers of impact — from pigment control to collagen boost.If you’re tired of chasing stubborn pigmentation or noticing your skin losing firmness, let’s build a personalized plan that actually works. Book a consultation and let’s get your skin back on track.#SylfirmX #RFmicroneedling #SkinRejuvenation #MelasmaTreatment #CollagenBoost #rosaceatreatment
Who said you can’t have lasers in the summer?! Refined lifted results and an uninterrupted lifestyle.We know how busy everyone’s schedule is in the summer which is why we love to offer Sofwave for that instant lift without the downtime.✔️ No downtime — resume your plans the same day✔️ Safe for sunny destinations✔️ Subtle, natural rejuvenation that builds over timeWhether you’re en route to your favourite summer hot spot or enjoying rooftop evenings in the city, Sofwave fits seamlessly into your routine—with no compromise on results.Because true luxury is looking your best—without pressing pause.#SofwaveSummer #EffortlessRefinement #LuxuryAesthetics #NoDowntimeNeeded
✨ Elevated beauty begins with balance.💣❣️Combination treatment of threads and Sofwave 🫂Symmetrical brows softly frame the face, enhance your natural features, and create effortless harmony. It’s a subtle detail — but it changes everything.✔️ Lifts and defines the eye area✔️ Enhances facial symmetry✔️ Complements a polished, natural lookIn the world of refined aesthetics, precision is power.Book a Consult with Dr. Mahsa to explore your options.#RefinedBeauty #BrowSymmetry #LuxuryAesthetics #BespokeBrows #TimelessBeauty #LessIsMore #FaceFramingElegance #ModernFemininity
Sylfirm X in Action at SAS Aesthetics ✨This dual-energy treatment combines micro-needling with radio frequency to lift, tighten, and regenerate your skin from within with no downtime.It targets:✔️Redness & rosacea✔️ Acne scars & pigmentation ✔️ Fine lines & crepey skin ✔️ Overall skin texture + tonePerformed by Dr Mahsa at SAS Aesthetics, Marylebone 🧖🏻♀️ Book your treatment via link in bio or DM us!#SylfirmX #SASAesthetics #SkinTightening #rosaceatreatment #collagen #microneedlingfacial
🖤 The Carbon Laser glow-upZaynn came in for a Carbon Laser Facial at SAS Aesthetics for a deep-cleansing, skin smoothing treatment that targets oil, texture and pigmentation in one go.✅Unclogs pores✅ Improves skin tone✅ Reduces excess oil✅ Instant glow, zero downtime 🧖🏻♀️ DM us to book your skin detox!#CarbonLaserFacial #LaserGlow #SkinRejuvenatiom #DeepCleanse #GlowingSkin #MensSkincare
✨ Say hello to skin regeneration from the inside out!Polynucleotide (PN) injections are the next-generation skin treatment making waves in regenerative aesthetics — and for good reason. Derived from purified DNA fragments (often from salmon or trout), PN works by activating your skin’s natural healing processes at a cellular level.So what makes PN a game changer for aging and pigmentation?✔️ Cellular Repair & RegenerationPN stimulates fibroblast activity, accelerating collagen and elastin production — two essential proteins for firm, youthful skin. Think smoother texture, improved elasticity, and reduced fine lines.✔️ Brightens Pigmentation & Uneven ToneBy encouraging cell turnover and improving skin health from within, PN helps to lighten hyperpigmentation, sun spots, and post-inflammatory marks — giving you a more even, radiant complexion.✔️ Deep Hydration & Skin Barrier SupportPN enhances the skin’s ability to retain moisture, restoring a healthy, dewy glow. It also strengthens the skin barrier, making it more resilient against environmental damage and inflammation.✔️ Anti-Inflammatory & ProtectiveIdeal for sensitive or compromised skin, PN reduces oxidative stress and calms inflammation, making it suitable even for those with rosacea or redness-prone skin.✔️ Natural, Long-Term ResultsRather than masking issues, PN works with your body’s biology to restore and rebuild — meaning results are gradual, but deeply rooted and long-lasting.—Want expert guidance tailored to your skin?Book a consultation with Dr. Mahsa Saleki, a trusted leader in advanced regenerative treatments. With her medical expertise and artistic approach, you’ll receive a personalised plan to restore youthful skin and even tone—safely and naturally.📍DM us or click the link in bio to start your journey with Dr. Saleki today.#SkinRejuvenation #PolynucleotideInjections #salmonsperm #salmonspermfacial
✨ Struggling with acne and oily skin?Discover how a Carbon Laser Facial can transform your skin! 🌟✅ Deep Pore Cleansing – Removes dirt, oil, and dead skin trapped in pores.✅ Reduces Acne & Blackheads – Targets active breakouts and minimizes future flare-ups.✅ Controls Sebum Production – Balances oily skin to help prevent clogged pores.✅ Smooths Skin Texture – Minimizes acne scars and evens out rough patches.✅ Kills Acne-Causing Bacteria – Uses laser energy to destroy P. acnes bacteria.✅ Shrinks Pores – Gives skin a refined, smoother look.✅ Boosts Collagen – Promotes healing and improves overall skin health.🌿 Ready to level up your skincare? Book your carbon laser facial today and start your journey to clearer, healthier skin! Click the link in our bio to schedule your appointment now. ✨
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